South Sudan has year-round mosquito activity, with peak risk during the rainy season from April through November. The entire country carries high malaria burden, with the Sudd wetlands, the Nile river system, and the Equatoria regions being particularly intense transmission areas. Juba also has significant risk.
Malaria (P. falciparum and P. vivax) is the primary concern, with South Sudan having one of the highest malaria burdens globally. Yellow fever is endemic. Ongoing conflict and displacement severely limit health access and vector control.
Anopheles gambiae and Anopheles funestus are the dominant malaria vectors. The vast Sudd wetland system provides some of the most extensive mosquito breeding habitat in Africa. Prevention is critical but challenging due to the conflict environment.
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Disease presence data is sourced from WHO, CDC, ECDC, and OpenDengue. This is not medical advice — consult a travel health professional before your trip.