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St. Louis Encephalitis

Severity: Low

St. Louis encephalitis is a rare mosquito-borne virus found only in the Americas. Most infections produce no symptoms at all, and symptomatic cases are uncommon. Severe encephalitis occurs primarily in elderly adults.

The virus is transmitted by Culex mosquitoes and circulates between birds and mosquitoes, with humans as incidental hosts. Small outbreaks occasionally occur in the United States during warm summer months, particularly in the Midwest and South.

There is no vaccine or specific treatment. The risk to travelers is extremely low, and standard evening bite precautions provide adequate protection.

Pathogen

Virus

Culex pipiens and Culex quinquefasciatus — night-biting house mosquitoes.

Risk Groups

Who is at risk
Low

Adults over 60 traveling in the Americas during summer months. Most infections are so mild they go completely unnoticed. There is no vaccine or specific treatment.

Symptoms

Most infections are asymptomaticFever, headache, dizzinessNausea and malaiseStiff neck and confusion in severe casesEncephalitis mainly in adults over 60Fatality rate under 10% in symptomatic cases

Mosquito species that transmit St. Louis Encephalitis

Culex pipiensCulex quinquefasciatus

Precautions

Use repellent during evening hours
Eliminate standing water around accommodation
Stay indoors at peak mosquito times (dusk to dawn)
Use window screens and air conditioning
Risk is very low for most travelers
No vaccine available — standard bite precautions suffice

Prevention essentials

Rare in tourists, peaks in summer in the Americas. Standard evening-hours repellent and intact window screens are enough for most travellers.

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Deep-dive guides
CDC SLE OverviewCDC Mosquito Prevention

Countries with St. Louis Encephalitis

St. Louis Encephalitis is recorded in 8 countries in our database. Click any country for the full Mozzwise briefing covering local seasonality, regional risk, and prevention.

ArgentinaBrazilCanadaJamaicaMexicoPanamaTrinidad and TobagoUnited States

Disease information is sourced from WHO, CDC, ECDC, and OpenDengue. Not medical advice. Personal decisions on diagnosis, treatment, vaccinations, or medication belong with a qualified healthcare professional.