United States Mosquito Season
The United States has highly variable mosquito seasons by region. The Gulf Coast and southern states have activity from March through November, while northern states have shorter seasons from May through September. Florida, Texas, Louisiana, and Hawaii have the highest mosquito-borne disease risk. The Southwest and mountain states have minimal activity.
WHO and CDC surveillance reports indicate that the seasonal mosquito risk in United States aligns with rainfall patterns and temperature, with peak transmission of United States's most-reported disease (Dengue Fever) typically following the wet season. Travel timing should account for these climatic windows.
Mosquito-Borne Diseases in United States
Mozzwise tracks 4 mosquito-borne diseases in United States based on WHO, CDC, and ECDC surveillance. Each entry below cross-links to a full Mozzwise disease briefing.
Dengue Fever is recorded in United States with moderate severity according to current surveillance. Travelers to endemic areas, young children, pregnant women, and people with prior dengue infection. A second infection with a different serotype carries a significantly higher risk of severe disease. Reported globally in: Tropical and subtropical regions worldwide — Southeast Asia, Latin America, Sub-Saharan Africa, Pacific Islands.
St. Louis Encephalitis is tracked as present in United States based on historical surveillance, though active transmission is not currently flagged. Adults over 60 traveling in the Americas during summer months. Most infections are so mild they go completely unnoticed. There is no vaccine or specific treatment. Reported globally in: Americas only — United States, Canada, Mexico, Argentina, Brazil, Caribbean.
West Nile Virus is tracked as present in United States based on historical surveillance, though active transmission is not currently flagged. Adults over 60 and immunocompromised travelers face the greatest risk of severe neuroinvasive disease. There is no vaccine and no specific treatment — taking precautions is your only protection. Reported globally in: Americas, Europe (expanding since 2010), Middle East, parts of Africa. Peak in late summer.
Zika Virus is tracked as present in United States based on historical surveillance, though active transmission is not currently flagged. Pregnant women and those planning pregnancy are the primary concern. The virus can cause devastating birth defects including microcephaly. Most adults recover without issues within a week. Reported globally in: Tropical Americas, Southeast Asia, Pacific Islands. Ongoing low-level transmission since the 2015-2016 epidemic.
How to Avoid Mosquito Bites in United States
Public health agencies converge on a layered approach to reducing mosquito bites in United States. The core recommendations across CDC, WHO, and ECDC are as follows.
Skin-applied repellents. CDC recommends EPA-registered repellents containing one of four tested active ingredients: DEET, picaridin, IR3535, or oil of lemon eucalyptus / para-menthane-diol. CDC advises applying sunscreen first and repellent on top, and reapplying at the interval stated on the product label.
Permethrin-treated clothing. WHO and CDC both recommend permethrin treatment of trousers, long-sleeved shirts, and socks for settings with sustained mosquito exposure. Permethrin binds to fabric and is effective against both Aedes and Anopheles species. It is not applied to skin.
Accommodation. Air-conditioned rooms with intact window screens substantially reduce indoor exposure. Bed nets — ideally permethrin-treated — are standard in open-air or budget accommodation. WHO emphasises removing standing water around accommodation, as even bottle caps, plant saucers, and water-storage containers can support Aedes breeding.
Timing. Aedes vectors active in cities and resort areas typically bite in daylight, with peaks in early morning and late afternoon. Anopheles vectors active in forested or rural areas typically bite at night.
For product reviews and brand comparisons see our [travel prevention guides](/guides). Personal decisions on repellent choice, vaccination, or any prescription medication remain with a qualified travel health professional.